CBD Dosage Info & FAQ

Below is our CBD oil guidance and suggestions. This is merely a guide as you

may modify your dosage based upon your personal needs.

How to take:
To achieve the best benefit from CBD, place the oil under the tongue and hold it there for 30-60 seconds. Swallow any remaining. Why?

a. There are capillaries under the tongue that absorb the CBD oil directly into the bloodstream.
b. Placing the dosage in food, beverage or swallowing whole, requires the CBD oil to process through the liver. Going through the liver results in reduced amounts of CBD in your blood, which is why we recommend placing the oil under the tongue.

Dosage - how much to take:

We suggest starting with 1 mL, 1-2 times per day or as needed (see adjust dosage section).

a. Take ideally on empty stomach.
b. Squirt the CBD oil under the tongue and hold it for 30-60 seconds. Most should absorb. Swallow any remaining.

Adjust Dosage:
Adjust your dosage. Why?

a. We all are different body sizes.
b. There is not a one size fits all approach when it comes to CBD oil. It’s okay to adjust your dosage, for example - 1.5 mL, .5 mL, 2 mL, etc. You won’t overdose on it.
c. Review your log for patterns (see below) and adjust accordingly.
d. You may need our extra strength CBD oil based on factors above, and that’s okay. Do what your body indicates.

Keep a Short Log
Identify patterns to help find the dosage best for your body. Note the following:

a. Dosage amount.
b. Time of dosage.
c. How you are feeling before taking CBD oil.
d. 1-2 hours after taking the CBD oil.
e. Outside factors such as the weather, work, kids, etc. (i.e. rainy, cold, busy at work, etc.)


Understanding CBD is very confusing, especially if you are just learning. Our Frequently Asked Questions are the best first step for CBD Education. We are always looking to improve our education page, so please feel free to reach out with further questions. If you have them, so do others.

What is CBD and what does CBD stand for?

CBD is short for cannabidiol (pronounced like can-uh-BIH-dee-all) and is a cannabinoid compound within the cannabis plant.

  • Cannabidiol (CBD) is found in both marijuana plants and hemp plants.
  • Hemp and marijuana are both cannabis plants. However, hemp and marijuana are different varieties of the Cannabis sativa plant species.
  • Hemp is from the Cannabis Sativa L strain.  Confusing right?  Think of it this way, you go to a garden center to buy geraniums.  There are different color geraniums, some different leaves, etc., however, they are all geraniums.  The difference is they come from different strains of the geranium plant.  This is the same concept when thinking about different Cannabis plants.  Hemp is from a different strain of cannabis plant that contains little to no THC (the part that gets you high).
  • Cannabinoids are chemical compounds within the cannabis plant.
  • CBD is one of over 100 cannabinoids that have been found on cannabis plants to date.
  • CBD does not get you high.

Is hemp CBD the same as marijuana CBD? Can you get high from hemp CBD?

No – they are different.  It’s confusing as the term “CBD” is used loosely.  CBD comes from the cannabis plant.  However:

  • Hemp and marijuana are both cannabis plants. But, hemp and marijuana are different strains of the cannabis sativa plant.
  • Marijuana cannabis plant strains contain tetrahydrocannabinol, also known as THC.  THC is the compound that produces the “high” effect.
  • Hemp is from the cannabis Sativa L strain, which contains little to no THC.
  • Confusing right?  Here’s a way to grasp it.  When you go to a garden center to buy geraniums for example.  There are plants with different colored pedals, some have different colored leaves, etc., however, they are all geraniums.  The difference is they come from different strains (seeds) of the geranium plant.  This is the same concept when thinking about different cannabis plants.  Hemp is from a different strain of cannabis plant that contains less than .3% THC or no THC. 
  • FDA regulations state hemp CBD products are legal if they contain .3% or less THC, which all Nature’s Gem CBD products comply with.

How does CBD work in our bodies?

CBD primarily interacts with the body’s endocannabinoid system (ECS).  

The endocannabinoid system (ECS), is a name given to the system (process), which ascertains how cannabinoids (such as CBD) interacts within the mind and body.  Within this system, there are two important receptors, CB1 and CB2, which affect different areas in our mind and body.   Now, if this makes sense – skip to CB1 receptors.

A more technical description:

The term “endo” is short for endogenous, meaning originating or produced within an organism, tissue or cell. Cannabinoid refers to a group of compounds that activate this particular system.  By way of example, imagine cell receptors in the body as a set of locks, each with a set of corresponding keys: chemical molecules called “agonists”. Each time an agonist is bound to a cell receptor it relays a message, giving the cell an instruction. The endocannabinoid system is the name for a series of cell receptors (locks) that respond to certain kinds of agonists (keys).

Two primary cell receptors make up the ECS: Cannabinoid Receptor 1 (CB1) and Cannabinoid Receptor 2 (CB2).

Endocannabinoids (or cannabinoids) are the “keys” for these receptors. Cannabinoid receptors (locks) respond to various cannabinoids (keys), which in turn produce distinctive effects within the body.

Too technical?  Yep, it is.   The cool stuff is learning about the receptors.  That’s where is all happens.

CB1 Receptors – 

CB1 Receptors are found throughout the human body, and there are a lot of them in the brain and spinal cord.

In the brain, for example, CB1 receptors are abundant in the hypothalamus (which regulates appetite) and in the amygdala, which is responsible for emotions, survival instinct and memory.

In addition, CB1 receptors are also found in nerve endings, where their role is to help reduce the feeling of pain.

It’s fascinating!  The brain and spinal cord send messages back and forth throughout the body. CB1 receptors are found within them BOTH.

CB2 Receptors – 

CB2 Receptors typically concentrate in the immune tissues and cells, such as white blood cells, the nervous system outside the brain and spinal cord, tonsils, spleen, digestive tract, and many of the body’s organs.  When these receptors are activated, one response they act upon is to reduce inflammation.  For this reason, it is largely believed these CB2 receptors may play a role in the body’s immune response to diseases, inflammation and certain medical conditions.

More and more research is being done in this area.  We support our researchers –  knowledge is power!

Why is a healthy Endocannabinoid System is important for our bodies?

Maintaining a healthy and balanced endocannabinoid system is important as this system essentially regulates all of the basic functions and patterns our body has to deal with including:

Where do we get our Hemp (CBD)?

All Nature’s Gem CBD products are made from carefully cultivated, grown, and harvested USA hemp, in accordance to strict USDA organic guidelines.

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